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Computed tomography (CT) scan of a chest wall showing sternal metastasis from melanoma (arrow). Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Typically they occur in the skin but may rarely occur in the mouth, intestines, or eye. In women they most commonly occur on the legs, while in men they are most common on the back. Sometimes they develop from a mole with concerning changes including an increase in size, irregular edges, change in color, itchiness, or skin breakdown. The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of skin pigment. Metastasis, or metastatic disease, is the spread of a cancer or disease from one organ or part to another not directly connected with it.
