. Karzinom der Schilddrüse im salmonoid Fische. Krebs; Kropf; Schilddrüse; Forelle. Karzinom der Schilddrüse in der SALMONOID FISCHE. 465 Durch die Behandlung unter exakt den gleichen Bedingungen vergleichbar Fisch mit Quecksilber in Form von HgCL. Dies hat den weiteren Vorteil, dass, wenn Quecksilber erweisen sollte eine ähnliche Wirkung auf die Schilddrüse, die für die Marine und Lenhart für Iod festgestellt zu haben, das Verhältnis von diese Wucherungen der Schilddrüse zu einer der Schwermetalle abhalten werden konnten - abgebaut, Quecksilber bereits gezeigt worden, eine hemmende und regressive Wirkung auf echte Neubildungen zu haben. Die Experim

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. Carcinoma of the thyroid in the salmonoid fishes. Cancer; Goiter; Thyroid gland; Trout. CARCINOMA OF THE THYROID IN SALMONOID FISHES. 465 by treating under exactly the same conditions comparable fish with mercury in the form of HgCL. This gave the further advantage that if mercury should prove to have a similar effect upon the thyroid to that determined by Marine and Lenhart for iodine, the relation of these growths of the thyroid to one of the heavy metals might be deter- mined, mercury already having been shown to have an inhibitory and regressive effect upon genuine neoplasms. The experiments were carried out in the summer of 1910 with the result, as may be seen by the accompanying tables, that mercury was found to have an effect upon the growing thyroid of the Salmonidae indistinguishable from that obtained with iodine, with the exception that mercury appeared to produce these results more certainly and more rapidly than did iodine. To further amplify the. Fig. 95.—Floating siphon. A is the siphon, B the frame, and C the container. The form of the frame is of course not essential, and should be adapted to the container. The illustrations show the glass tubing of much larger size than is neces- sary or practical>le in small siphons. Small tubing is preferable. comparison, during the summer of 1911 experiments with arsenic, an element long known to have a favorable influence upon genuine neoplasms, were carried out, using arsenic in the form of ASjOj. These results are also sufficiently set forth in the tables. Experiments were begun by determining the toxicity of the iodine to trout when added to the water in the form of the pure element already dissolved in distilled water and then added to the dissolved potassium salt. The uncombined iodine is much more toxic than the potassium iodide. Lake trout fry were killed in less than 20 hours by one part of free iodine added to 400, 000 parts of tap water. Dilutions of i to i ;00o, ooo are safe, perhaps because the

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